Assay for trichothecenes

Details Assay for trichothecenes Assay for trichothecenes

1987-04-28

1989-11-07

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

436 93, 436518, 436538, 436544, 436815, 436822, 436825, G01N 33531, G01N 33543, G01N 33537, B63H 108

Patent

active

048792489

ABSTRACT:
An immunoassay for trichothecenes that have at least three hydroxyl groups at specified positions is disclosed. It relies on developing antibodies to close trichothecene variants that are missing at least one of the hydroxyl groups, and then using these antibodies to test specimens in which the trichothecene has been converted to the variant (usually to the OAC variant). For example, DON and T-2 tetraol can be assayed for using this invention.

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