Assay for the determination of creatinine

Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-n

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436175, G01N 3370

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active

045297088

ABSTRACT:
An improved colorimetric assay method and reagent composition for the quantitative determination of creatinine in biological fluid specimens in the presence of protein, in which the specimen is reacted directly with an alkaline picrate reagent composition which contains an iron chelator, preferably ethylenediaminetetraacetic acid, thereby significantly suppressing interference from bilirubin and improving reagent stability.

REFERENCES:
patent: 3894843 (1975-07-01), Jarvis
patent: 4111657 (1978-09-01), Denney et al.
Tagesson et al., Clinical Chemistry, vol. 26, No. 3, 1980, p. 520.
Osberg et al., Clinical Chemistry, vol. 24, No. 7, pp. 1196-1197, 1978.
Wako, Chemical Abstracts, vol. 96, 1982, No. 96: 196193q.
Wako, Chemical Abstracts, vol. 94, 1981, No. 94: 135591e.
Lolekha et al., Clinica Chimica Acta, 107(1980) 97-104.
Daugherty et al., Clinical Chemistry, vol. 24, No. 2, 1978, pp. 392-393.

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