Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1985-09-23
1989-11-14
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
424 88, 514 8, 530397, 530398, 530412, 530413, C07K 302, C07K 314, C07K 320, C07K 328
Patent
active
048809144
ABSTRACT:
A method to obtain a substantially pure and stable hLH-hCG receptor from gonadal cells is disclosed. The characteristics of the purified receptor are disclosed. The receptor, in addition to being used as receptor in an enzyme- or dye-receptor assay for hLH and/or hCG, can be used to purify hLH or hCG used in the preparation of standard dye-hormone or enzyme-hormone complexes. These complexes can be used in enzyme- or dye-immunoassays, as well as the receptor assay.
REFERENCES:
Metsikko, K., et al., FEBS Lett., 106(1), 193-196, (1979).
Dufau, M. L. et al., J. Biol. Chem., 250(12), 4822-4824, (1975).
Wimalasend, J. et al., J. Biol. Chem., 261(20), 9416-9420, (1986).
Rathnam Premila
Saxena Brij B.
Cornell Research Foundation Inc.
Nucker Christine M.
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