Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Patent
1995-06-21
1997-03-04
Hutzell, Paula K.
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
435 79, 435 7021, 4351722, 435975, 436503, 436548, 436811, 436822, 5303879, 5303889, G01N 3353
Patent
active
056078625
ABSTRACT:
A method for assaying bone resorption rates which consists of quantitating the concentration of peptide fragments derived from bone collagen, found in a body fluid is disclosed. The method includes immunometric assay, fluorometric assay and electrochemical titration. The structure of specific peptide fragments having 3-hydroxypyridinium cross-links found in urine of Paget's disease patients and procedures for making monoclonal antibodies is described.
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Fietzek, P. P. and Kuhn, K., "The Coval
Hutzell Paula K.
Washington Research Foundation
Wolski Susan C.
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