Assay for glutathiane transferase using polyhaloaryl-substituted

Details Assay for glutathiane transferase using polyhaloaryl-substituted Assay for glutathiane transferase using polyhaloaryl-substituted

1997-04-25

1998-06-30

Kunz, Gary L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving transferase

530300, 549223, 549228, A61K 3806, C07D31182

Patent

active

057732361

ABSTRACT:
The subject invention describes compounds containing a polyhalogenated aryl moiety. The compounds of the invention are particularly useful for the assay of a variety of enzymes, including intracellular enzymes. The subject invention also describes assays for glutathione and/or glutathione transferase enzymes. Selected compounds of the invention are particularly useful for improving the retention of fluorescent products of enzyme metabolism in cells.

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