Assay for determining the efficacy of paf-acether and/or LA-paf

Details Assay for determining the efficacy of paf-acether and/or LA-paf Assay for determining the efficacy of paf-acether and/or LA-paf

1992-03-03

1994-10-18

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

514 77, 514220, 514468, C12Q 102, A01N 5726, A01N 4362

Patent

active

053567919

ABSTRACT:
According to the invention, a procedure for determining the efficacy of paf-acether and/or LA-paf antagonists using lipoproteins, lipoprotein-associated paf (LA-paf), cholesterol or a mixture of lipoproteins, LA-paf and cholesterol is disclosed.

REFERENCES:
patent: 4734280 (1988-03-01), Braquet
patent: 4914096 (1990-04-01), Houlihan
Korth, R., Comparison of Human Endothelial Cells . . . Federation Proceedings, 46(3) Mar. 1, 1987, p. 444.
Korth R., Comparison of 3 Paf-Acether Receptor Antagonist . . . European J of Pharm 152 (1988) 101-110.
Korth R., Interaction of the Paf Antagonist WEB 2086 . . . Br J Pharmacol (1989) 98 653-661.
O'Neill Co., The Effect of Inhibitors of Platelet . . . Lipids 26(12) 1991 pp. 1011-1014.
Benveniste J., Lipoprotein Bound Paf-Acether . . . Federation Proceedings 46(4) Mar. 5, 1987 p. 1468.

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