Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving blood clotting factor
Patent
1993-09-15
1995-12-05
Beisner, William H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving blood clotting factor
435 4, 435 791, 436 63, 436 69, 436164, 514 2, C12Q 156, C12Q 100
Patent
active
054728525
ABSTRACT:
An assay useful for detecting the propensity of patients for thrombotic disease, especially patients having the lupus anticoagulant or antiphospholipid antibodies, is described. The assay is conducted on patient and control plasma in the presence and absence of exogenous Protein C with a membrane source comprising phosphatidylethanolamine and phosphatidylserine. Patients at risk exhibit test results indicating activated Protein C function is inhibited.
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Esmon Charles T.
Smirnov Mikhail D.
Beisner William H.
Oklahoma Medical Research Foundation
Williams Jane
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