Assay for beta-adrenergic antagonists and antibody therefor

Details Assay for beta-adrenergic antagonists and antibody therefor Assay for beta-adrenergic antagonists and antibody therefor

1980-06-23

1982-06-01

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 260112B, 424 12, 424 85, G01N 3356, G01N 3358, C07G 700

Patent

active

043327877

ABSTRACT:
Body fluids are assayed for aryloxypropylamine beta-adrenergic antagonists and/or their active metabolites by agglutination reaction with antibody for the antagonist and/or active metabolite. The antibody is produced from an antigen comprising a conjugate of an immunogenic protein linked by a diazo moiety to an aryloxypropylamine beta-adrenergic antagonist.

REFERENCES:
patent: 4026879 (1977-05-01), Spector
patent: 4070492 (1978-01-01), Spector
Mueller et al., From Radio Immunoassay of Drugs and Hormones in Cardiovascular Medicine, Ed. Albertine et al., Elsevier/North-Holland, The Netherlands, 1979, pp. 93-106.

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