Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1994-10-12
1998-09-08
Huff, Sheela
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 72, 436 63, 436 64, G01N 33574, G01N 3353, G01N 33567, G01N 3348
Patent
active
058043969
ABSTRACT:
Method for identifying an agent for treatment of a proliferative disorder, comprising the steps of assaying a potential agent for activity in inhibition of signal transduction by a HER2/HER3 or HER2/HER4 or HER3/HER4 heterodimer. Method of screening for an agent that selectively inhibits the kinase activity of a heterodimer having one catalytically inactive component.
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Eyler Yvonne
Huff Sheela
Sugen Inc.
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