Assay for a putative regulator of cell cycle progression

Details Assay for a putative regulator of cell cycle progression Assay for a putative regulator of cell cycle progression

1998-11-10

2000-12-12

McKelvey, Terry

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 29, C12Q 168, C12Q 102

Patent

active

061596914

ABSTRACT:
The present invention provides nuclear localisation signals derived from the DP-3 and E2F-1 transcription factors and the use of these signals in assays for regulators of cell cycle progression. Such assays involve using the signals to direct a marker gene to the nucleus and determining whether the nuclear localisation of the marker is disrupted by the presence of a putative regulator.

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