Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1992-09-15
1994-05-03
Saunders, David
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
422 56, 422 57, 422 58, 435 79, 435 792, 435 793, 435 794, 435970, 435967, 436164, 436169, 436514, 436528, 436530, 436805, 436810, G01N 33537, G01N 33538, G01N 33543, G01N 33558
Patent
active
053087755
ABSTRACT:
The novel analytical devices and methods of the present invention involve dual pathway devices which provide for the confirmation of sandwich or competitive assay results. In a self-confirming sandwich assay, the labeled analyte complex becomes immobilized within a first pathway at an assay capture site to indicate the presence or amount of an analyte in the test sample. In a second pathway, a confirmatory reagent blocks the binding of the analyte or labeled analyte complex to a confirming assay site, thereby confirming that the presence of label in the assay capture site indicates a positive test sample. In a self-confirming competitive assay, a confirmed positive result is one in which the device displays a decrease in signal or no signal at the assay capture site, and the confirming assay site displays a detectable signal.
REFERENCES:
patent: 4046514 (1977-09-01), Johnston et al.
patent: 4849338 (1989-07-01), Litman et al.
patent: 4900663 (1990-02-01), Wie et al.
patent: 5081013 (1992-01-01), Rovelli et al.
Maggio, Enzyme-Immunoassays, (Boca Raton, Florida, CRC Press Inc.,), 1980.
Donovan James J.
Worobec Stephen W.
Abbott Laboratories
Chin Christopher L.
Curry Daniel R.
Saunders David
Steele Gregory W.
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