Assay device and method for chemical or biological screening

Details Assay device and method for chemical or biological screening Assay device and method for chemical or biological screening

2006-11-21

2006-11-21

Beisner, William H. (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C435S305300, C435S808000, C435S033000, C422S105000, C422S942000, C436S165000, C359S398000

Reexamination Certificate

active

07138270

ABSTRACT:
An assay device (1) comprises a base (2) and glass plate lid (3). The base (2) has an array of shallow microwells (4), each having a flat rim (9), all rims being co-planar. When the lid (3) is placed on the base (2) a thin capillary gap (10) is formed on each rim, acting as a liquid seal for a microwell chamber. The liquid is excess sample liquid and further excess is accommodated in overspill cavities (6) between the microwells (4). Because of the liquid seal and shallow configuration the benefits of microfluidic devices are achieved together with the handling convenience and use of conventional detection equipment of conventional microplate devices.

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