Chemistry: analytical and immunological testing – Involving diffusion or migration of antigen or antibody
Patent
1995-06-05
2000-01-25
Chin, Christopher L.
Chemistry: analytical and immunological testing
Involving diffusion or migration of antigen or antibody
422 56, 422 57, 422 58, 422 61, 435 71, 435 72, 435 79, 435 793, 435 794, 435 795, 4352877, 4352879, 4352884, 4352885, 435969, 435970, 435973, 436518, 436524, 436807, 436809, 436810, G01N 33558, G01N 33543
Patent
active
060177675
ABSTRACT:
A chromatographic assay device for use with immunoassays allows rapid and convenient assays of analytes of biological interest, and permits extractions to be carried out in situ, avoiding the use of separate extraction vessels. The device has a wide dynamic range and avoids interference from particulates or colored components. In one form, the device comprises: (1) a first opposable component comprising a sample preparation means adapted to receive a sample to be assayed; and (2) a second opposable component comprising a chromatographic medium. The first and second opposable components can be brought into opposition so as to cause the sample preparation means to apply the sample to be tested to the chromatographic medium. Preferably, the analyte is detected with a visually detectable label. Other variations of the device vary the arrangement of components to provide optimal chromatography for a variety of analytes, as well as to permit bidirectional chromatography. The devices can be incorporated in test kits, and assay methods using the devices are also disclosed.
REFERENCES:
patent: Re30267 (1980-05-01), Bruschi
patent: Re31006 (1982-08-01), Schuurs et al.
patent: 1926299 (1933-09-01), Monk
patent: 3078031 (1963-02-01), Kauffeld
patent: 3186623 (1965-06-01), Guyer
patent: 3307770 (1967-03-01), Wysocki
patent: 3420205 (1969-01-01), Morison
patent: 3437449 (1969-04-01), Luckey
patent: 3475129 (1969-10-01), Peurifoy
patent: 3551555 (1970-12-01), Schuurs
patent: 3720760 (1973-03-01), Bennich et al.
patent: 3723064 (1973-03-01), Liotta
patent: 3798004 (1974-03-01), Zerachia et al.
patent: 3811840 (1974-05-01), Bauer et al.
patent: 3867517 (1975-02-01), Ling
patent: 3888629 (1975-06-01), Bagshawe
patent: 3893808 (1975-07-01), Campbell
patent: 3901657 (1975-08-01), Lightfoot
patent: 3902964 (1975-09-01), Greenspan
patent: 3915647 (1975-10-01), Wright
patent: 3926564 (1975-12-01), Giaever
patent: 3932220 (1976-01-01), Liotta
patent: 3933594 (1976-01-01), Milligan et al.
patent: 3933997 (1976-01-01), Hersh et al.
patent: 3935074 (1976-01-01), Rubenstein et al.
patent: 3949064 (1976-04-01), Bornstein et al.
patent: 3951332 (1976-04-01), Torbeck
patent: 3960499 (1976-06-01), White
patent: 3961894 (1976-06-01), Gordon
patent: 3966897 (1976-06-01), Renn et al.
patent: 3975162 (1976-08-01), Renn et al.
patent: 3979509 (1976-09-01), Giaever
patent: 3981981 (1976-09-01), Reunanen
patent: 3984533 (1976-10-01), Uzgiris
patent: 3985867 (1976-10-01), Redshaw
patent: 3989591 (1976-11-01), Liotta
patent: 3992158 (1976-11-01), Przybylowicz
patent: 3993451 (1976-11-01), Verbeck
patent: 3996006 (1976-12-01), Pagano
patent: 4012198 (1977-03-01), Finter et al.
patent: 4016043 (1977-04-01), Schuurs
patent: 4017597 (1977-04-01), Reynolds
patent: 4018662 (1977-04-01), Ruhenstroth-Bauer et al.
patent: 4020151 (1977-04-01), Bolz et al.
patent: 4038485 (1977-07-01), Johnston et al.
patent: 4039652 (1977-08-01), Adams et al.
patent: 4042335 (1977-08-01), Clement
patent: 4046514 (1977-09-01), Johnston et al.
patent: 4053284 (1977-10-01), Posch
patent: 4054646 (1977-10-01), Giaever
patent: 4059407 (1977-11-01), Hochstrasser
patent: 4065383 (1977-12-01), Skare et al.
patent: 4066403 (1978-01-01), Bruschi
patent: 4067774 (1978-01-01), Rubenstein et al.
patent: 4067959 (1978-01-01), Bolz
patent: 4087326 (1978-05-01), Kereluk
patent: 4087332 (1978-05-01), Hansen
patent: 4094647 (1978-06-01), Deutsch et al.
patent: 4108729 (1978-08-01), Mennen
patent: 4108972 (1978-08-01), Dreyer
patent: 4108976 (1978-08-01), Reese
patent: 4110079 (1978-08-01), Schaeffer et al.
patent: 4116638 (1978-09-01), Kenoff
patent: 4123224 (1978-10-01), Givner et al.
patent: 4123509 (1978-10-01), Banik et al.
patent: 4128399 (1978-12-01), Liotta et al.
patent: 4129417 (1978-12-01), White
patent: 4130462 (1978-12-01), Rubenstein et al.
patent: 4133639 (1979-01-01), Harte
patent: 4134792 (1979-01-01), Boguslaski et al.
patent: 4144306 (1979-03-01), Figueras
patent: 4145186 (1979-03-01), Andersen
patent: 4145406 (1979-03-01), Schick et al.
patent: 4153668 (1979-05-01), Hill et al.
patent: 4157323 (1979-06-01), Yen et al.
patent: 4160008 (1979-07-01), Fenocketti et al.
patent: 4166102 (1979-08-01), Johnson
patent: 4168146 (1979-09-01), Grubb et al.
patent: 4169138 (1979-09-01), Jonsson
patent: 4175923 (1979-11-01), Friend
patent: 4177253 (1979-12-01), Davies et al.
patent: 4180383 (1979-12-01), Johnson
patent: 4189304 (1980-02-01), Adams et al.
patent: 4200690 (1980-04-01), Root et al.
patent: 4205058 (1980-05-01), Wagner et al.
patent: 4205952 (1980-06-01), Cais
patent: 4210418 (1980-07-01), Brown et al.
patent: 4219335 (1980-08-01), Ebersole
patent: 4223089 (1980-09-01), Rothe et al.
patent: 4228237 (1980-10-01), Hevey et al.
patent: 4233029 (1980-11-01), Columbus
patent: 4233402 (1980-11-01), Maggio et al.
patent: 4235601 (1980-11-01), Deutsch et al.
patent: 4237234 (1980-12-01), Meunier
patent: 4238565 (1980-12-01), Hornby et al.
patent: 4243749 (1981-01-01), Sadeh et al.
patent: 4244694 (1981-01-01), Farina et al.
patent: 4246339 (1981-01-01), Cole et al.
patent: 4248829 (1981-02-01), Kitajima et al.
patent: 4248965 (1981-02-01), Mochida et al.
patent: 4254082 (1981-03-01), Schick et al.
patent: 4254083 (1981-03-01), Columbus
patent: 4255384 (1981-03-01), Kitajima et al.
patent: 4256693 (1981-03-01), Kondo et al.
patent: 4258001 (1981-03-01), Pierce et al.
patent: 4268270 (1981-05-01), Gabbay et al.
patent: 4270921 (1981-06-01), Graas
patent: 4271119 (1981-06-01), Columbus
patent: 4274832 (1981-06-01), Wu et al.
patent: 4275149 (1981-06-01), Litman et al.
patent: 4279617 (1981-07-01), Masson et al.
patent: 4279885 (1981-07-01), Reese et al.
patent: 4280816 (1981-07-01), Elahi
patent: 4281061 (1981-07-01), Zuk et al.
patent: 4288228 (1981-09-01), Oberhardt
patent: 4298345 (1981-11-01), Sodickson et al.
patent: 4298685 (1981-11-01), Parikh et al.
patent: 4299916 (1981-11-01), Litman et al.
patent: 4301139 (1981-11-01), Feingers et al.
patent: 4305720 (1981-12-01), Bernstein
patent: 4305721 (1981-12-01), Bernstein
patent: 4305924 (1981-12-01), Piasio et al.
patent: 4313734 (1982-02-01), Leuvering
patent: 4315907 (1982-02-01), Fridlender et al.
patent: 4318707 (1982-03-01), Litman et al.
patent: 4323536 (1982-04-01), Columbus
patent: 4332783 (1982-06-01), Pernice et al.
patent: 4333733 (1982-06-01), Sanford et al.
patent: 4337065 (1982-06-01), Hiratsuka et al.
patent: 4338094 (1982-07-01), Elahi
patent: 4347312 (1982-08-01), Brown et al.
patent: 4357311 (1982-11-01), Schutt
patent: 4361537 (1982-11-01), Deutsch et al.
patent: 4362697 (1982-12-01), Tabb et al.
patent: 4363874 (1982-12-01), Greenquist
patent: 4365970 (1982-12-01), Lawrence et al.
patent: 4366241 (1982-12-01), Tom et al.
patent: 4373932 (1983-02-01), Gribnau et al.
patent: 4374925 (1983-02-01), Litmanm et al.
patent: 4376110 (1983-03-01), David et al.
patent: 4380580 (1983-04-01), Boguslaski et al.
patent: 4390343 (1983-06-01), Walter
patent: 4391904 (1983-07-01), Litman et al.
patent: 4407943 (1983-10-01), Cole et al.
patent: 4411518 (1983-10-01), Meserol et al.
patent: 4425438 (1984-01-01), Cole et al.
patent: 4426451 (1984-01-01), Columbus
patent: 4435504 (1984-03-01), Zuk et al.
patent: 4442204 (1984-04-01), Greenquist et al.
patent: 4444193 (1984-04-01), Fogt et al.
patent: 4446232 (1984-05-01), Liotta
patent: 4447526 (1984-05-01), Rupchock et al.
patent: 4447529 (1984-05-01), Greenquist et al.
patent: 4447546 (1984-05-01), Hirschfeld
patent: 4450231 (1984-05-01), Ozkan
patent: 4452901 (1984-06-01), Gordon et al.
patent: 4459358 (1984-07-01), Berke
patent: 4461829 (1984-07-01), Greenquist
patent: 4464552 (1984-08-01), Pawlowski
patent: 4472498 (1984-09-01), Masuda et al.
patent: 4474878 (1984-10-01), Halbert et al.
patent: 4477575 (1984-10-01), Vogel et al.
patent: 4486530 (1984-12-01), David et al.
patent: 4504585 (1985-03-01), Reynolds
patent: 4506009 (1985-03-01), Lenhoff et al.
patent: 4514507 (1985-04-01), Secher
patent: 4517288 (1985-05-01), Giegel et al.
patent: 4533629 (1985-08-01), Litman et al.
patent: 4540659 (1985-09-01), Litman et al.
patent: 4550075 (1985-10-01
Beckman Coulter Inc.
Chin Christopher L.
Kivinski Margaret A.
May William H.
Nguyen Bao-Thuy L.
LandOfFree
Assay device does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Assay device, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Assay device will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2315267