Assay based on particles, which specifically bind with...

Details Assay based on particles, which specifically bind with... Assay based on particles, which specifically bind with...

2002-04-17

2009-08-11

Gakh, Yelena G (Department: 1797)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C436S524000, C436S527000, C436S528000, C436S531000, C436S532000, C436S533000, C436S534000, C436S056000, C436S164000, C436S166000

Reexamination Certificate

active

07572642

ABSTRACT:
The invention provides a particle comprising a surface, wherein a portion of the surface is capable of emitting electromagnetic radiation and another portion of the surface is capable of emitting a differential electromagnetic radiation (either different intensity, different frequency or no radiation), and wherein the arrangement of said portions of the surface defines a spatially distributed code for identifying the particle. The invention also provides method of manufacturing a particle having an identifying code comprising providing a particle with a functionalized surface which comprises functional binding moieties and selectively removing a plurality of the functional binding moieties from the surface to create a pattern of functionalized and differentially-functionalized zones on the surface. Various liquid-based assay methods employing the particle of the invention and a kit comprising the particle of the invention are also disclosed.

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