Assay and reaction vessel with a compartmentalized solubilizatio

Details Assay and reaction vessel with a compartmentalized solubilizatio Assay and reaction vessel with a compartmentalized solubilizatio

1993-03-17

1994-12-13

Kepplinger, Esther M.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

422 58, 422 55, 422 61, 422 72, 422 8209, 422 93, 422102, 435 71, 435 725, 436523, 436531, 436539, 436 67, 436165, 436169, G01N 3372, G01N 3122, G01N 33546, G01N 33539

Patent

active

053729480

ABSTRACT:
Disclosed are a method and device for performing sequential analytical reactions involving a first dry reagent and a second dry reagent comprised of two or more components having different rates of solubilization. The invention enables one to fully solubilize the components of the second reagent before they are brought into contact with each other to thereby avoid interference with the reaction kinetics which result when one or both of the components are not fully dissolved prior to their being brought into contact. The invention is especially useful in conjunction with immunoassay formats involving latex bound antibodies and polymeric agglutinators.

REFERENCES:
patent: 4847209 (1989-07-01), Lewis et al.
patent: 4918025 (1990-04-01), Grenner
patent: 4970171 (1990-11-01), Messenger et al.
patent: 4990075 (1991-02-01), Wogoman
patent: 5084397 (1992-01-01), Siddons et al.
patent: 5104813 (1992-04-01), Besemer et al.
patent: 5162237 (1992-11-01), Messenger et al.

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