Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-03-18
2000-07-18
Prouty, Rebecca E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 4352521, 435 6, 4352561, 536 231, C12P 2106, C12N 1500, C12N 120, C12N 114, C07H 2102
Patent
active
060905816
ABSTRACT:
This invention relates to newly identified auxotrophs, polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production and isolation of such polynucleotides and polypeptides. More particularly, the polynucleotides and polypeptides of the present invention have been putatively identified as being very important to the growth and/or reproduction of Aspergillus fumigatus.
REFERENCES:
D'Enfert et al. "Attenuated Virulence of Uridine-Uracil Auxotrophs of Aspergillus fumigatus" Infection and Immunity, Oct. 1996, vol. 64, No. 10, pp. 4401-4405, see entire document.
Sikorski et al. "A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae" Genetics, May 1989, vol. 122, pp. 19-27, see entire document.
Sikorski et al. "In vitro Mutagenesis Plasmid Shuffling: From Cloned Gene to Mutant Yeast" Methods in Enzymology, 1991, vol. 194, pp. 302-318, see entire document.
Grant Alan J.
Millenium Pharmaceuticals, Inc.
Monshipouri M.
Olstein Elliot M.
Prouty Rebecca E.
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