Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1987-10-01
1989-03-07
Kight, John
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560 41, 560169, 562567, 562571, C07K 506, C07K 106
Patent
active
048108170
ABSTRACT:
Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
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Chmurny Alan B.
Gross Akiva T.
Kupper Robert J.
Roberts Rowena L.
Kight John
Nutter Nathan M.
Trinker Steven T.
W. R. Grace & Co.
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