Aspartic acid derivatives

Details Aspartic acid derivatives Aspartic acid derivatives

1988-09-08

1991-12-24

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560163, 560116, 560125, 560 24, 560 28, 530330, C07C27134

Patent

active

050754904

ABSTRACT:
New compounds N-.alpha.-9-fluorenylmethoxycarbonyl-aspartic acid-.beta.-1-adamantyl esters are stable under the basic condition of the normal peptide condensation process and do not form succinimide. Peptides containing aspartic acid can be synthesized with high purity and at high yields by using N-.alpha.-9-fluorenylmethoxycarbonyl-aspartic acid-.beta.-1-adamantyl ester.

REFERENCES:
Okada et al., Chemical Abstracts, vol. 110, entry 76038d (1988).

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