Asparaginases

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S252300, C435S254110, C435S254300, C435S320100, C426S049000, C536S023200, C536S023100

Reexamination Certificate

active

07871806

ABSTRACT:
The invention relates to new asparaginases having improved properties, preferably improved thermotolerance, such as improved activity at high temperatures and/or improved thermostability. The invention also relates to DNA sequences encoding such improved asparaginases, their production in a recombinant host cell, as well as methods of using the asparaginases, in particular for reduction of acrylamide in foods. The invention furthermore relates to methods of generating and preparing asparaginase variants having improved properties.

REFERENCES:
patent: 1 704 782 (2006-09-01), None
patent: WO2004/026042 (2004-04-01), None
patent: WO2004/030468 (2004-04-01), None
patent: WO2004/032648 (2004-04-01), None
Lubkowski et al, “Atomic resolution structure ofErwinia chrysanthemiL-asparaginase”, Acta Cryst. D, vol. 59, pp. 84-92 (2003).
Watanabe K. et al, “Designing Thermostable Proteins: Ancestral Mutants of 3-Isopropylmalate Dehydrogenase Designed by using a Phylogenetic Tree”, Journal of Molecular Biology, vol. 335, pp. 664-674 (2006).
Kotzia et al, Journal of Biotechnology, vol. 119, pp. 309-323 (2005).
Liu et al, Protein Engineering, vol. 16, No. 1, pp. 19-25 (2003).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Asparaginases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Asparaginases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Asparaginases will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2708801

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.