ASP2

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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Reexamination Certificate

active

06870030

ABSTRACT:
ASP2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ASP2 polypeptides and polynucleotides in the design of protocols for the treatment of Alzheimer's Disease, cancer, and prohormone processing, among others, and diagnostic assays for such conditions.

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NCBI Accession Q9Y5Z0 (Human Asp1). Beta Secretase 2 Precursor (Beta-Site APP-Cleaving Enzyme 2) (Aspartyl Protease 1) (ASP 1) (ASP1) (Membrane-Associated Aspartic Protease 1) (Memapsin-1), Jan. 15, 2002.
NCBI Accession AAF13714. Memapsin 1 [Homo sapiens], Feb. 16, 2000.
NCBI Accession NP 036237. Beta-Site APP-Cleaving Enzyme 2 [Homo Sapiens], Dec. 21, 2003.
NCBI Accession AAF26368. Transmembrane Aspartic Proteinase Asp 1 [Homo sapiens], Jul. 6, 2000.
NCBI Accession AAF17078. Aspartyl Protease 1 [Homo sapiens], Dec. 12, 1999.
NCBI Accession NM 012105. Homo sapiens Beta-Site APP-Cleaving Enzyme 2 (BACE2), mRNA; May 21, 2002.
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NCBI Accession: P56817 (Human Asp2). Beta-Secretase Precursor (Beta-Site App Cleaving Enzyme) (Beta-Site Amyloid Precursor Protein Cleaving Enzyme) (Aspartyl Protease 2)(Asp 2)(Asp2)(Membrane-Associated Aspartic Protease2) (Memapsin-2), Jun. 15, 2002.
NCBI Accession XP 006430. Beta-Sitte APP-Cleaving Enzyme (Homo sapiens), Jul. 16, 2001.
NCBI Accession A59090. Aspartic Proteinase (EC 3.4.23.-) BACE Precursor -Human, May 11, 2000.
NCBI Accession NP 036236. Beta-Site APP-Cleaving Enzyme (Homo sapiens), Jan. 15, 2003.
NCBI Accession AAF04142. Beta-Site APP Cleaving Enzyme (Homo sapiens); Oct. 26, 1999.
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NCBI Accession 1FKNA. Structures of Beta-Secretase Complexed with Inhibitor; Aug. 9, 2000.
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NCBI Accession AAF26367. Transmembrane Aspartic Proteinase Asp2 (Homo sapiens), Jan. 19, 2000.
NCBI Accession AAF18982. APP beta-Secretase (Homo sapiens); Dec. 19, 1999.
NCBI Accession AAF 17079. Aspartyl Protease 2 (Homo sapiens), Dec. 12, 1999.
NCBI Accession NT 009334. Homo sapiens Chromosome 11 Working Draft Sequence Segment, complete sequence, Aug. 27, 2001.
NCB

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