Ascorbic acid synthesis

Details Ascorbic acid synthesis Ascorbic acid synthesis

1977-06-03

1978-09-05

Jaisle, Cecilia M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603437, C07D30732, C07D31904

Patent

active

041119584

ABSTRACT:
Ascorbic acid is prepared from a 1,4-lactone selected from gulono-1,4-lactone, galactono-1,4-lactone, idono-1,4-lactone and talono-1,4-lactone by a process comprising protection of the hydroxyl groups of the lactone so as to form an intermediate having a free hydroxyl group at either, but not both, the 2- or 3-position, oxidizing this free hydroxyl group to a keto group and hydrolyzing the oxidized intermediate to remove the hydroxyl-protecting groups.

REFERENCES:
kitahara et al., Agr. Biol. Chem. 38(11), 2189-2190, 1974.

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