Ascorbic acid intermediates and process enzymes

Details Ascorbic acid intermediates and process enzymes Ascorbic acid intermediates and process enzymes

1984-06-14

1988-07-19

Tarcza, John Edward

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435143, 4351723, 435190, 435253, 435320, 935 14, 935 29, 935 60, C12P 1934, C12P 750, C12N 1500, C12N 904

Patent

active

047585145

ABSTRACT:
2-keto-L-gluonic acid (2-KLG) is prepared from 2,5-diketo-D-gluconic acid (2,5-DKG) using a microorganism containing the enzyme 2,5-DKG reductase produced by an expression plasmid encoding a gene for the enzyme. The product, 2-KLG is a precursor for the synthesis of ascorbic acid (vitamin C).

REFERENCES:
patent: Re30872 (1982-02-01), Sonoyama et al.
patent: 3907639 (1975-09-01), Makover et al.
patent: 4245049 (1981-01-01), Kita et al.
patent: 4259444 (1981-03-01), Chakrabarty
patent: 4452890 (1984-05-01), Tsuchida et al.
patent: 4465773 (1984-08-01), Dean et al.

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