Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1987-05-21
1991-04-16
Warren, Charles F.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435190, 4351723, 435 91, 435843, 4353201, 435847, 435823, 43525232, 4352523, C12P 760, C12P 1934, C12N 904, C12N 1500, C12N 100, C12N 113
Patent
active
050081934
ABSTRACT:
Methods for producing ascorbic acid using recombinant means comprising the transfer of genetic material by conjugation, a host cell lacking, entirely or to such an extent as not to be commercially useful, one or more enzymes in the metabolic path converting glucose to 2 keto-L-gulonic acid.
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Sonoyama et al., "Production of 2-Keto-L-Gulonic Acid from D-Glucose by Two-Stage Fermentation", Applied and Environmental Microbiology, vol. 43, No. 5, May 1982, pp. 1064-1069.
Adachi et al., "Crystallization and Characterization of NADP-Dependent D-Glucose Dehydrogenase from Gluconobacter suboxydans", Agric. Biol. Chem., 44(2), 1980, pp. 301-308.
Anderson Stephen
Light David R.
Marks Cara
Rastetter William H.
Dreger Ginger R.
Genentech Inc.
Low Christopher S. F.
Warren Charles F.
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