Ascorbic acid intermediates

Details Ascorbic acid intermediates Ascorbic acid intermediates

1980-05-05

1981-08-11

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D31904

Patent

active

042833400

ABSTRACT:
A synthetic route to ascorbic acid is provided in which a 3,5:4,6-protected derivative of gulonic acid is prepared from gulono-1,4-lactone. Oxidation of the derivative and hydrolysis of the resulting product affords 2-ketogulonic acid or ester thereof which can be readily converted to ascorbic acid by known methods.

REFERENCES:
patent: 2039929 (1936-05-01), Reichstein
patent: 2190167 (1940-02-01), Zima
patent: 2207991 (1940-07-01), Pasternack et al.
patent: 2301811 (1942-11-01), Reichstein
patent: 2847421 (1958-08-01), D'Addieco
patent: 3463790 (1969-08-01), Black et al.
patent: 3682925 (1972-08-01), Den Hollander et al.
patent: 4111958 (1978-09-01), Crawford
Matsui et al., Yakugaku Zasshi, 86.110-113, (1966).
Meguro et al., Biol. Chem., vol. 36, No. 12, pp. 2075-2079.
Hulyakar et al., Can. J. Chem., vol. 41, pp. 1898-1904, (1963).
Chem. Abstracts, 40:1453', (1946).
Ogura et al., J. Org. Chem., vol. 37, No. 1, pp. 72-75 (1972).
Matsui et al., Chem. Pharm. Bull., 16(7), pp. 1288-1293, (1968).
Ness et al., J.A.C.S., 73, pp. 4759-4761, (1951).
Kohn et al., J.A.C.S., 87, pp. 5475-5480, (1965).
Upson et al., J.A.C.S., 58, pp. 2549-2552, (1936).
Kohn et al., J.A.C.S., 86, pp. 1457-1458, (1964).
Chem. Abstracts 53:3084h.
Chem. Abstracts Collective Index 1962-1966, p. 10,580s.

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