Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-05-15
1999-02-09
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 23, 514 53, 514 54, A61K 3134, A61K 3170, A61K 31715
Patent
active
058695257
ABSTRACT:
An L-ascorbic acid drug for intracerebral administration comprising one or more stable activity L-ascorbic acid compounds and one or more blood brainbarrier deobstruents. Also disclosed is a method for increasing intracerebral concentration of L-ascorbic acid in a human being comprising administering by injection an L-ascorbic acid drug comprising one or more stable activity L-ascorbic acid compounds. Additionally disclosed is a method for increasing intracerebral concentration of L-ascorbic acid in a human being comprising administering by injection an L-ascorbic acid drug comprising one or more stable activity L-ascorbic acid compounds and one or more blood brainbarrier deobstruents. Also disclosed is a method for treating diseases or disorders that result from intracerebral bloodstream inhibition or intracerebral bloodstream lowering comprising administering by injection to a person in need of such treatment, a dosage effective amount of an L-ascorbic acid drug comprising one or more stable activity L-ascorbic acid compounds. Additionally disclosed is a method for treating diseases or disorders that result from intracerebral bloodstream inhibition or intracerebral bloodstream lowering comprising administering by injection to a person in need of such treatment, a dosage effective amount of an L-ascorbic acid drug comprising one or more stable activity L-ascorbic acid compounds and one or more blood brainbarrier deobstruents.
REFERENCES:
Yamamoto et al. Biochim Bioplays Acta (1990)1035 (1), 44-50.
Schreiber et al. Sb. Lek. (1990), 92 (2-3), 85-8 (Abstract).
Masek et al. Vopr. Pitan (1977), (6), 46-50 (Abstract).
Izquierdo et al. J. Pharm. Pharmacol. (1968), 20 (3), 210-14 (Abstract).
Ito Shinobu
Miwa Nobuhiko
Ogata Eiji
Showa Denko Kabushiki Kaisha
Spivack Phyllis G.
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