Arylvinyl cyclopropyl ketones

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603405R, C07C 4984, C07D31706

Patent

active

041827295

ABSTRACT:
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester. The intermediate iodides are prepared by condensing a methyl cyclopropyl ketone with an aromatic aldehyde to give an arylvinyl cyclopropyl ketone, reducing the latter to an arylethyl cyclopropyl carbinol or arylvinyl cyclopropyl carbinol, treating the carbinol with phosphorus tribromide and then with zinc bromide to give an arylalkyl or arylalkenyl bromide, and then replacing the bromine atom by iodine.

REFERENCES:
patent: 3458565 (1969-07-01), Bicking
patent: 3878200 (1975-04-01), Diana et al.
patent: 4005103 (1977-01-01), Teulon

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