Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo

Details Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo

1991-02-04

1991-12-03

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514533, 514539, 514543, 514562, 514569, 514571, 514602, 514604, 514605, 514822, 514824, 514826, A61K 3141, A61K 31235, A61K 3124, A61K 31195, A61K 3119, A61K 3118

Patent

active

050700995

ABSTRACT:
Arylthioalkylphenylcarboxylic acids are provided which have the structure ##STR1## wherein Ar represents an aryl group including phenyl or naphthyl which may or may not include one or more substituents, X is COOR where R is hydrogen, alkali metal, or lower alkyl, or X is 5-tetrazolyl or ##STR2## wherein R.sup.1 is lower alkyl or aryl, p is 1 to 5, and m is 1 to 4. These compounds are cardiovascular agents which exhibit thromboxane antagonist activity and thus are useful in the treatment of thrombotic and vasospastic diseases.

REFERENCES:
patent: 4258058 (1981-03-01), Witte
patent: 4443477 (1984-04-01), Witte
patent: 4752613 (1988-06-01), Floyd
patent: 4752616 (1988-06-01), Hall
patent: 4755524 (1988-07-01), Mueller

Affiliated with

Also associated with

Rating

Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arylthioalkylphenyl carboxylic acids, derivatives thereof, compo will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1697223