Arylsulphonamides, pharmaceutical compositions containing these

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

5462764, 5462804, C07D21316

Patent

active

056819617

ABSTRACT:
The invention relates to new arylsulphonamides of the formula ##STR1## (wherein A, B and R.sub.1 to R.sub.6 are as defined in claim 1, the enantiomers, the cis- and trans-isomers thereof where R.sub.4 and R.sub.5 together represent a carbon-carbon bond, and the addition salts thereof, more particularly for pharmaceutical use the physiologically acceptable addition salts thereof with inorganic or organic bases, if R.sub.6 represents a hydroxy group) which have useful pharmacological properties, particularly antithrombotic activities and thromboxane-mediating activities. Furthermore, the new compounds are also thromboxane antagonists (TRA) and thromboxane synthesis inhibitors (TSH). They also have an effect on PGE.sub.2 production.

REFERENCES:
patent: 4317828 (1982-03-01), Tanouchi et al.
patent: 4518602 (1985-05-01), Terao et al.
patent: 4563446 (1986-01-01), Terao et al.
patent: 4760068 (1988-07-01), Terao et al.
patent: 4902698 (1990-02-01), Cooper
patent: 4929754 (1990-05-01), Nickl et al.
patent: 4997847 (1991-03-01), Ife et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Arylsulphonamides, pharmaceutical compositions containing these does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arylsulphonamides, pharmaceutical compositions containing these , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arylsulphonamides, pharmaceutical compositions containing these will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1027320

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.