Arylsulfonylimidazolone derivatives as an antitumor agent

Details Arylsulfonylimidazolone derivatives as an antitumor agent Arylsulfonylimidazolone derivatives as an antitumor agent

1997-08-21

1999-07-27

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5483121, A61K 31415, C07D40312

Patent

active

059291036

ABSTRACT:
The present invention relates to a novel arylsulfonylimidazolone derivative represented by the following formula (I) which shows a superior antineoplastic activity in contrast to the known sulfonylurea antitumor agents as well as little side effect: ##STR1## and its pharmaceutically acceptable salt and stereoisomer, in which ----, R.sub.1, and R.sub.2 are as defined in the specification.

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