Arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds

Details Arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds Arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds

1975-08-15

1976-12-21

Higel, Floyd D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260545R, 260556AR, 424321, C07C14378, A61K 3118

Patent

active

039988791

ABSTRACT:
A new class of arylsulfonylcarbamoyl-1,3-cyclohexanediones and arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds are disclosed. These substances have hypoglycemic or hyperglycemic properties and are of value in controlling abnormal blood sugar levels. The arylsulfonylcarbamoyl derivatives of 1,3-dicarbonylalicyclic and acyclic compounds are prepared by reacting an arylsulfonylisocyanate with a 1,3-dicarbonylalicyclic or acyclic reactant. Typical embodiments are 2-(N-p-chlorobenzenesulfonylcarbamoyl)-5,5-dimethylcyclohexane-1,3-dione and 5-(1-ethylpropyl)-2-(N-p-chlorobenzenesulfonylcarbamoyl)-1,3-cyclohexanedi one.

REFERENCES:
patent: 3298917 (1967-01-01), Bicking
patent: 3917718 (1975-11-01), Collins

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