Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-07-27
1999-11-30
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514255, 544 584, 544159, 544386, 548540, 548953, A61K 31495, A61K 31535, C07D295192
Patent
active
059943513
ABSTRACT:
A compound of the formula ##STR1## wherein n, X, R.sup.3, R.sup.4 and Ar are as defined above, useful in the treatment of a condition selected from the group consisting of arthritis, cancer, tissue ulceration, restenosis, periodontal disease, epidermolysis bullosa, scleritis and other diseases characterized by matrix metalloproteinase activity, AIDS, sepsis, septic shock and other diseases involving the production of TNF.
REFERENCES:
Parker et al,, The Development of 27023A. Poster P73 at the Seventh International Conference of the Inflammation Research Association, Sep. 25-29, 1994X.
Rizzi James P.
Robinson Ralph P.
Butterfield Garth
Ginsburg Paul H.
Pfizer Inc.
Ramsuer Robert W.
Richardson Peter C.
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