Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1998-08-06
2000-08-22
O'Sullivan, Peter
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
564 90, 564 91, 564 89, 5142375, 5142382, 514255, 514459, 514538, 514539, 514542, 514562, 514602, 514604, 514824, 514921, 544160, 544391, 544402, 549424, 560 13, 562430, A61K 3135, A61K 31216, A61K 3150, A61K 315375
Patent
active
061073377
ABSTRACT:
A compound of the formula ##STR1## wherein n, X, R.sup.3, R.sup.4 and Ar are as defined above, useful in the treatment of a condition selected from the group consisting of arthritis, cancer, tissue ulceration, restenosis, periodontal disease, epidermolysis bullosa, scleritis, bone resorption, loosening of artificial joint implants, atherosclerosis, multiple sclerosis, occular angiogenisis and other diseases characterized by matrix metalloproteinase activity, AIDS, sepsis, septic shock and other diseases involving the production of TNF.
Ginsburg Paul H.
Jacobs Seth H.
O'Sullivan Peter
Pfizer Inc.
Richardson Peter C.
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