Arylsulfonamido-substituted hydroxamic acids

Details Arylsulfonamido-substituted hydroxamic acids Arylsulfonamido-substituted hydroxamic acids

1994-11-03

1996-09-03

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544 581, 544168, 544130, 544131, 544133, 540524, 540531, 514604, 546175, 546194, 546247, 546209, 546265, 5462834, 5462821, 546333, 546337, 5462804, 5462844, 5462817, 5462751, 548205, 5483351, 5483381, 549 13, 549 65, 549426, 564 84, 564 90, 564 92, 564 94, 5142378, 514311, 514331, 514332, 514341, 514365, 514396, 514406, 514432, 514445, 514451, 514602, C07D21342, A61K 3144

Patent

active

055524192

ABSTRACT:
The invention relates to the compounds of formula I ##STR1## pharmaceutically acceptable prodrug derivatives and pharmaceutically acceptable salts thereof; methods for preparation thereof; pharmaceutical compositions comprising said compounds; and a method of inhibiting matrix-degrading metalloproteinase and of treating matrix-degrading metalloproteinase dependent conditions in mammals using such compounds.

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