Arylsecocholadiene derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai

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552653, A61K 359, C07C40100

Patent

active

061536059

ABSTRACT:
Compounds of formula (I) ##STR1## as defined by the specification. The compounds are useful in the treatment or prevention of vitamin D dependent disorders, particularly psoriasis, basal cell carcinomas, disorders of keratinization and keratosis, leukemia, osteoporosis, hyperparathyroidism accompanying renal failure, transplant rejection and graft vs. host disease.

REFERENCES:
patent: 5447924 (1995-09-01), Bretting
patent: 5817648 (1998-10-01), Kutner et al.
patent: 5843928 (1998-12-01), Deluca et al.
patent: 5945410 (1999-08-01), Deluca et al.
Grue-Soerensen, et al. Proc. Workshop, Vitamin D, vol. 9, 1994 pp. 75-76.

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