Arylpiperidinopropanol and arylpiprazinopropanol derivatives...

Details Arylpiperidinopropanol and arylpiprazinopropanol derivatives... Arylpiperidinopropanol and arylpiprazinopropanol derivatives...

2005-01-04

2005-01-04

Bernhardt, Emily (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S331000, C514S317000, C546S217000, C546S232000, C546S240000

Reexamination Certificate

active

06838470

ABSTRACT:
A compound having the formula (I) or its salt, hydrate, hydrate salt or solvate:wherein R1to R4independently represent H, halogen, OH, alkoxy, optionally substituted alkyl, aryl, or aralkyl group, R5represents H, optionally substituted alkyl, aryl, or aralkyl group, E1represents O, S, or —NR6, where R6represents H, an optionally substituted alkyl, aryl, or aralkyl group, E2represents O, S, or —NR7, where R7represents H, an optionally substituted alkyl, aryl, or aralkyl group, A represents CH, C(OH), or N, X represents H, halogen, alkoxy, or an optionally substituted alkyl group, and Q represents an optionally substituted phenyl group, phenoxy, phenylmethyl, or cycloalkyloxy group, where when E1represents O or S, E2does not represent O or S, which has an action of suppressing the cytotoxic Ca2+overload and lipid peroxidation and effective for pharmaceutical preparation for the alleviation and treatment of symptoms due to ischemic diseases, etc.

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