Arylpiperazinylalkoxy derivatives of cyclic imides

Details Arylpiperazinylalkoxy derivatives of cyclic imides Arylpiperazinylalkoxy derivatives of cyclic imides

1988-03-17

1988-10-25

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514253, 544230, 544284, 544295, 544363, 544364, 544368, 544376, 544394, A61K 31495, C07D40114, C07D40314, C07D40514

Patent

active

047804661

ABSTRACT:
There are disclosed compounds of the formula ##STR1## wherein the group A is ##STR2## where R.sub.1 and R.sub.2 are each independently hydrogen or loweralkyl, or R.sub.1 +R.sub.2 =(CH.sub.2).sub.m, m being 2 to 6, p is 1 or 2, and each X is independently hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, amino, loweralkylamino, diloweralkylamino, trifluoromethyl or loweralkylthio; W is O, H.sub.2 or [H, OH]; n is 2, 3 or 4; and R.sub.3 is ##STR3## where q is 1 or 2 and each Y is independently hydrogen, loweralkyl, loweralkoxy, halogen, hydroxy, nitro, amino, loweralkylamino, diloweralkylamino, trifluoromethyl or loweralkylthio, which are useful as antipsychotic, anxiolytic and analgesic agents.

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Yevich et al., "J. Med. Chem.", 1968, vol. 29, pp. 359-369.
Diehl et al., "J. Med. Chem.", vol. 8, 1965, pp. 274-275.

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