Arylpiperazines having activity at the serotonin 1 A receptor

Details Arylpiperazines having activity at the serotonin 1 A receptor Arylpiperazines having activity at the serotonin 1 A receptor

2007-12-18

2007-12-18

Richter, Johann (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S360000, C544S392000

Reexamination Certificate

active

11225541

ABSTRACT:
A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1Areceptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.

REFERENCES:
patent: 4536516 (1985-08-01), Harper et al.
patent: 7001908 (2006-02-01), Godfrey et al.
patent: 637389 (1962-09-01), None
patent: 1013907 (1965-12-01), None
patent: A-06-239865 (1994-08-01), None
patent: A-06-293803 (1994-10-01), None
patent: WO 92/06082 (1992-04-01), None
patent: WO 94/21610 (1994-09-01), None
patent: WO 01/72731 (2001-10-01), None
Balducci et al., Psychopharmacology (Berl), Apr. 2003; 167(1):28-36.
Paquette, et al., J. Org. Chem., 54 (1989), pp. 5044-5053.
Pitsikas et al., Brain Res, Sep. 5, 2003; 983(1-2):215-22).
Rasmussen, J. and V. Rocco, Annual Reports Med. Chem., 30(1), 1 (1995).
Robichaud et al., Annual Reports in Medicinal Chemistry, 11-20 (2000).
Saxena, Pramod R., Pharmac. Ther., 66, 339-368 (1995).
Schechter et al., Curr Pharm Des. 2002, 8(2):139-145.
Gaodeng Xuexiao Huaxue Xuebao, 1991, vol. 12, No. 2, p. 210-212.
Translation of Japan Official Action, dated Aug. 3, 2007.

Affiliated with

Also associated with

Rating

Arylpiperazines having activity at the serotonin 1 A receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arylpiperazines having activity at the serotonin 1 A receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arylpiperazines having activity at the serotonin 1 A receptor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3885855