Aryloxypropanolaminotetralins, a process for their preparation a

Details Aryloxypropanolaminotetralins, a process for their preparation a Aryloxypropanolaminotetralins, a process for their preparation a

1992-01-09

1993-10-19

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

5142262, 5142368, 514241, 514255, 514311, 514312, 514351, 514361, 514373, 514379, 514381, 514394, 514396, 514407, 514411, 514415, 514418, 514434, 514443, 514445, 514454, 514456, 514457, 514466, 514469, 514470, 514479, 514510, 514561, 514597, 514630, 544 51, 544134, 546 81, 546176, 546334, 548136, 548209, 548241, 5483667, 548251, 5483235, 5483431, 548326, 5483701, 54830604, 5483435, 548418, 548484, 5483625, 5483611, 5483044, 549 40, 549 23, 549 51, 549 65, 549391, 549285, 549366, 549387, 549466, 549469, 5494

Patent

active

052545954

ABSTRACT:
Aryloxypropanolaminotetralins with beta-antagonist activity of the formula ##STR1## wherein R is hydrogen, hydroxy or methoxy and Ar is an optionally substituted aromatic or heteroaromatic group, in optically active or inactive form as well as their acid addition salts are described.
A process for their preparation and pharmaceutical compositions containing the compounds of formula (i) or their pharmaceutically acceptable acid addition salts, are also described.

REFERENCES:
patent: 3466325 (1969-09-01), Brandstrom et al.
patent: 4016202 (1977-04-01), Koppe et al.
patent: 4853383 (1989-08-01), Baldwin et al.
patent: 4952730 (1990-08-01), Leuchs et al.

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