Aryloxy and aryloxyalklazetidines as antiarrhythmic and anticonv

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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548950, 548952, A61K 31395, C07D20504

Patent

active

051303094

ABSTRACT:
Methods of treating cardiac arrhythmias and convulsions in warm-blooded animas and pharmaceutical compositions therefor are disclosed. The compounds useful in the methods of treatment and compositions are represented by the formula ##STR1## where n is 0 to 3 and R is H, C.sub.1 -C.sub.4 alkyl or arylalkyl and Ar is phenyl or substituted phenyl.

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Rodebaugh, R. M. and Cromwell, N. H. J. Het Chem. 8, 19-24 (1971).
Okutani, T.; Kaneko, T. and Masuda, K. Chem. Pharm. Bull. 22(7), 1490-1497 (1974).

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