Aryloxy aminobutanols, their preparation and use thereof

Details Aryloxy aminobutanols, their preparation and use thereof Aryloxy aminobutanols, their preparation and use thereof

1976-05-19

1978-01-31

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029356, 26029383, 26029384, 26032685, 26050118, 260562R, 260562P, 260562A, 2605707, 260519, 424267, 424274, 424330, 560252, C07C 9116, A61K 31135, C07C 9318

Patent

active

040715523

ABSTRACT:
Disclosed herein are compounds of the formula ##STR1## in which Ar is phenyl or 1-naphthyl; R.sup.1 is hydrogen or lower alkyl; and R.sup.2 and R.sup.3 are either the same or different selected from the group consisting of hydrogen or lower alkyl; with the proviso that when R.sup.1 is lower alkyl then R.sup.2 is the same lower alkyl. The compounds are antidepressant agents and methods for their preparation and use also are disclosed.

REFERENCES:
patent: 3203992 (1965-08-01), Kunz et al.
patent: 3954872 (1976-05-01), Koppe et al.
Howe, J. Med. Chem., 13(3), pp. 398-403 (1970).
Harsanyi et al., Chem. Absts., vol. 83, 192806(a) (1975).

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