Arylmorpholine, preparation and use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544106, 544107, 544178, A61K 31535, C07D26530

Patent

active

056483473

ABSTRACT:
A method for the treatment of depression in a human being, the method comprising administering to the human being an antidepressant effective amount of a compound of the following formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein R and R.sup.1 are independently hydrogen or fluorine.

REFERENCES:
patent: 2997469 (1961-08-01), Heel et al.
patent: 3117967 (1964-01-01), Anderson et al.
patent: 4360519 (1982-11-01), White et al.
patent: 4576944 (1986-03-01), Lafon
patent: 4714699 (1987-12-01), Lafon
patent: 4803200 (1989-02-01), Munson, Jr. et al.
patent: 5104870 (1992-04-01), Kelley et al.
Rekka et al., "Synthesis, Physicochemical Properties and Biological Studies of Some Substituted 2-alkoxy-4-methy-morpholines", Eur. J. Med. Chem, 24, 179-185 (1989).
Tyle, "Iontophoretic Devices for Drug Delivery", Pharmaceutical Research, 3(6), 318 (1986).
Lutz et al., "1,2-Diphenyl Amino Ketones and Alcohols. Condensation of Amines With Unsymmetrically Substituted Benzoins and Related Reactions", J. Org. Chem, 21, 49 (1956).
Lutz et al., "Substituted-Amino Ketones and Alcohols Related to 4,4'-Dichlorobenzoin", J. Am. Chem, Soc., 71, 478 (1949).
Lutz et al., "Secondary and Tertiary Amino Ketones and Alcohols Derived from Desoxybenzoin and 1,2-Diphenylethanol. Ring-chain Tautomerism of .alpha.-(.beta.-Hydroxyethylamino) Ketones", J. Am., Chem, Soc., 70, 2015 (1948).
European Search Report EP90311851.1, 11 Dec. 1990.

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