Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1990-06-20
1991-09-10
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564368, 564337, 564338, 516209, 516236, 516240, 544 87, 544158, 544170, 544174, 5142318, 5142392, 5142388, 514320, 514317, A61K 31135, C07C21108
Patent
active
050474324
ABSTRACT:
Compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof; in which R.sub.1 and R.sub.2, which are the same or different, are H or an optionally substituted hydrocarbon group or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form an optionally substituted heterocyclic ring;
REFERENCES:
patent: 3054822 (1962-09-01), Schorr et al.
patent: 3573304 (1971-03-01), Eberle et al.
patent: 3706764 (1972-12-01), Nakanishi et al.
patent: 4443449 (1984-04-01), Jeffery et al.
patent: 4522828 (1985-06-01), Jeffery et al.
patent: 4629727 (1986-12-01), Kozlik et al.
"Synthesis of New Heterocycles: Part XV--Synthesis of Novel Cyclic and Acyclic Sulphamides", Ind. Jrnl. Chem., vol. 14B, pp. 766-769 (1976).
"Substituted Acetic Acids XXXII--Army. Khim. Zhurnal", vol. 29, No. 2, pp. 194-199 (1976), A. Mndzhoyan et al.
Israel J. Chem. 5(5), pp. 223-229 (1967), "1-phenylcycloalkylamine Derivatives I", A. Kalir et al.
"1-Phenylcycloalkylamine Derivatives II", J. Med. Chem. 12, pp. 473-477 (1969), A. Kalir, H. Edery, Z. Pelah, D. Balderman and Gila Porath.
"1-Phenylcycloalkylamine Derivatives III", Israel J. Chem. 13(2), pp. 125-136 (1975), A. Kalir, S. Sadeh, H. Karoly, E. Shirin, D. Balderman.
Goodman and Gillman's "The Pharmacological Basics of Therapeutics", 7 ed., pp. 12 to 21 (1978).
Usdin, "Metabolic Pathways for Antipsychotic Drugs", Psychopharmacology, pp. 895-902 (1978).
Clarke, "Isolation and Identification of Drugs", Pharmaceutical Press, 1986, pp. 284-292.
D. H. Schroeder, J. Clin. Psychiatry 44 (5) Sect. 2, pp. 79-81 (1983).
Poyner "In Consideration of Active Metabolites", J. Clin. Pharmacology, 27, pp. 167-168 (1987).
"Bupropion: Possible Role of Major Metabolites in Mode of Action", Clin. Pharmacol. Ther. (37, No. 2, 187,1985), Cooper et al.
Housley John R.
Jeffery James E.
Johnston David N.
Sargent Bruce J.
Raymond Richard L.
Russell Mark
The Boots Company PLC
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