Arylcycloalkyl derivatives having branched side chains,...

Details Arylcycloalkyl derivatives having branched side chains,... Arylcycloalkyl derivatives having branched side chains,...

2007-05-22

2007-05-22

Page, Thurman K. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C562S405000, C562S433000, C562S442000, C562S451000, C560S024000, C560S037000

Reexamination Certificate

active

10789323

ABSTRACT:
Arylcycloalkyl derivatives having branched side chains, processes for their preparation and their use as pharmaceuticalsThe invention relates to arylcycloalkyl derivatives having branched side chains and to their physiologically acceptable salts and physiologically functional derivatives.What is described are compounds of the formula I,in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistence is involved.

REFERENCES:
patent: 6221633 (2001-04-01), Ertl
patent: 6221897 (2001-04-01), Frick
patent: 6245744 (2001-06-01), Frick
patent: 6277831 (2001-08-01), Frick
patent: 6342512 (2002-01-01), Kirsch
patent: 6525069 (2003-02-01), Ko et al.
patent: 38 73 992 (1988-12-01), None
patent: 0 293 880 (1988-12-01), None
patent: 0 462 884 (2001-12-01), None
patent: 2002201171 (2002-07-01), None
patent: 20002201127 (2002-07-01), None
patent: WO 94/18183 (1994-08-01), None
patent: WO 94/18184 (1994-08-01), None
patent: WO 96/38428 (1996-12-01), None
patent: WO 97/26265 (1997-07-01), None
patent: WO 97/41097 (1997-11-01), None
patent: WO 98/08871 (1998-03-01), None
patent: WO 98/19998 (1998-05-01), None
patent: WO 99/03861 (1999-01-01), None
patent: WO 99/15525 (1999-04-01), None
patent: WO 99/61431 (1999-12-01), None
patent: WO 99/62871 (1999-12-01), None
patent: WO 99/62872 (1999-12-01), None
patent: WO 99/67278 (1999-12-01), None
patent: WO 99/67279 (1999-12-01), None
patent: WO 00/40569 (2000-07-01), None
patent: WO 00/63208 (2000-10-01), None
patent: WO 00/64876 (2000-11-01), None
patent: WO 00/64888 (2000-11-01), None
patent: WO 00/66585 (2000-11-01), None
patent: WO 00/71549 (2000-11-01), None
patent: WO 00/78312 (2000-12-01), None
patent: WO 01/04146 (2001-01-01), None
patent: WO 01/09111 (2001-02-01), None
patent: WO 01/21602 (2001-03-01), None
patent: WO 01/40169 (2001-06-01), None
patent: WO 01/40171 (2001-06-01), None
patent: WO 01/72290 (2001-10-01), None
patent: WO 01/81327 (2001-11-01), None
patent: WO 01/83451 (2001-11-01), None
patent: WO 01/85695 (2001-11-01), None
patent: WO 01/91752 (2001-12-01), None
patent: WO 01/94300 (2001-12-01), None
patent: WO 02/38541 (2002-05-01), None
patent: WO 02/46146 (2002-06-01), None
patent: WO 02/50027 (2002-06-01), None
patent: WO 02/064549 (2002-08-01), None
patent: WO 02/096864 (2002-12-01), None
patent: WO 03/004458 (2003-01-01), None
patent: WO 03/020269 (2003-03-01), None
patent: WO 03/040174 (2003-05-01), None
patent: WO 03/066581 (2003-08-01), None
patent: WO 03/084922 (2003-10-01), None
patent: WO 03/084923 (2003-10-01), None
patent: WO 03/104188 (2003-12-01), None
Asakawa A et al., Cocaine-Amphetamine-Regulated Transcript Influences Energy Metabolism Anxiety and Gastric Emptying in Mice, Hormone and Metabolic Research; vol. 33(9); 2001; pp. 554-558.
Berger Joel et al., The Mechanisms of Action of PPARs, Annul. Rev. Med.; vol. 53; 2002; pp. 409-435.
Fruchart Jean-Charles et al., PPARs, Metabolic Disease and Atherosclerosis, Pharmacological Research; vol. 44, No. 5; 2001' pp. 345-352.
Kersten Sander et al., Roles of PPARs in Health and Disease, Nature; vol. 405; May 25, 2000; pp. 421-424.
Kliewer Steven A et al., Peroxisome Proliferator-Activated Receptors: From Genes to Physiology, Recent Prog. Horm Res.; vol. 56; 2001; pp. 239-263.
Lee Daniel W et al., Leptin agonists as a potential approach to the treatment of obesity, Drugs of the Future; vol. 26(9); 2001; pp. 873-881.
Motojima Kiyoto, Peroxisome Proliferator-Activated Receptor (PPAR): Structure, Mechanisms of Activation and Diverse Functions, Cell Structure and Function; vol. 18; 1993; pp. 267-277.
Okada Hiroshi et al., Synthesis and Antitumor Activities of Prodrugs of Benzoylphenylureas, Chem. Pharm. Bull.; vol. 42(1); 1994; pp. 57-61.
Pineda Torra Ines et al., Peroxisome Proliferator-activated Receptors: from Transcriptional Control to Clinical Practice, Curr. Opin. Lipidol; vol. 12; 2001; pp. 245-254.
Pineda Torra Ines et al., Peroxisome proliferator-activated receptor alpha in metabolic disease, Inflammation, atherosclerosis and aging, Curr. Opin. Lipidol; vol. 10; 1999; pp. 151-159.
Vidal-Puig A et al., Regulation of PPAR y Gene Expression by Nutrition and Obesity in Rodents, J. Clin. Invest.; vol. 97, No. 11, 1996; pp. 2553-2561.
Wilson Timothy M. et al., The PPARs; From Orphan Receptors to Drug Discovery, Journal of Medicinal Chemistry; vol. 43, No. 4; 2000; pp. 527-550.
Zunft H,. J. F. et al., Carob Pulp Preparation for Treatment of Hypercholesterolemia, Advances in Natural Therapy; vol. 18, No. 5; Sep.-Oct. 2001; pp. 230-236.

Affiliated with

Also associated with

Rating

Arylcycloalkyl derivatives having branched side chains,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Arylcycloalkyl derivatives having branched side chains,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Arylcycloalkyl derivatives having branched side chains,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3794352