Arylcycloalkanepolyalkylamine ligands

Details Arylcycloalkanepolyalkylamine ligands Arylcycloalkanepolyalkylamine ligands

1991-09-12

1993-06-29

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514424, 514426, 514427, 548531, 548535, 548537, 548538, 548539, 548541, 548556, 548557, 548558, 548560, 548561, 548562, 546563, A01N 4336, C07D20730

Patent

active

052235300

ABSTRACT:
Novel arylcycloalkanepolyalkylamines useful as anti-psychotic, anti-ischemia, anti-stroke, anti-dementia and anti-convulsant agents. These arylcycloalkanepolyalkylamines are selective high-affinity ligands to the sigma binding-sites containing three basic units: arylcycloalkyl group, an amine group and an intermediate chain. Their preparation and use for treatment of psychoses, ischemia, stroke, dementia and convulsions are also disclosed.

REFERENCES:
patent: 4966901 (1990-10-01), Zoller et al.

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