Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-07-20
1995-10-17
Springer, David B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
546152, 546157, 546158, C07D40704, C07D40904, C07D21522, A61K 3147
Patent
active
054592712
ABSTRACT:
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
REFERENCES:
patent: 5134148 (1992-07-01), Crawley et al.
Dube Daniel
Friesen Richard W.
Girard Yves
Merck Frosst Canada Inc.
Rose David L.
Springer David B.
Yang Mollie M.
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