(Arylamidoaryl)squaramide compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S314000

Reexamination Certificate

active

07829717

ABSTRACT:
Compounds represented by Formula (I):or a pharmaceutically acceptable salt or N-oxide thereof, wherein A, Q, Y, R5, m and J are defined herein, are useful in the treatment of tumors and cancers such as mastocytosis/mast cell leukemia, gastrointestinal stromal tumors (GIST), germ cell tumors, small cell lung carcinoma (SCLC), sinonasal natural killer/T-cell lymphoma, testicular cancer (seminoma), thyroid carcinoma, malignant melanoma, ovarian carcinoma, adenoid cystic carcinoma, acute myelogenous leukemia (AML), breast carcinoma, pediatric T-cell acute lymphoblastic leukemia, neuroblastoma, mast cell leukemia, angiosarcoma, anaplastic large cell lymphoma, endometrial carcinoma, and prostate carcinoma.

REFERENCES:
patent: 2002/0016461 (2002-02-01), Albers
Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design, 2005, Wiley-VCH Verlag GmbH & Co. KGaA, Wienheim.
International Search Report in PCT/US2005/033319.
Written Opinion of the International Searching Authority in PCT/US2005/033319.
International Preliminary Report on Patentability in PCT/US2005/033319.

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