Arylamide derivatives for treating hyperlipemia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514252, 514255, 514316, 514318, 514326, 514327, 544365, 544379, 544391, 546189, 546193, 546213, 546214, 546217, 546226, 546262, 546282, 546314, A61K 31445, C07D21140, C07D21174, C07D29510

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054119723

ABSTRACT:
An arylamide derivative of formula (1), a salt thereof and a therapeutic agent for hyperlipemia which comprises the derivative or salt: ##STR1## wherein Ar represents a group ##STR2## a naphthyl group, a pyridinyl group, a furyl group, a thienyl group, a quinolyl group or an indolyl group; Y represents a group ##STR3## and Q represents --O-- or a single bond, Z represents an alkylene group, and R.sup.4 represents a hydroxyl group, an alkoxy group or a group --NH(CH.sub.2).sub.m COOH, useful for the treatment and prevention of hyperlipemia due to their excellent cholesterol reducing action, triglyceride reducing action and high safety.

REFERENCES:
patent: 3801581 (1974-04-01), Rossi et al.
patent: 4981853 (1991-01-01), Mueller
patent: 5159081 (1992-10-01), Cantrell
Database WPI, Derwent Publications, AN 86-098620, JP-A-61 044 817, Mar. 4, 1986.

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