Arylalkyl and aryloxyalkyl phosphonates and use as antiviral age

Details Arylalkyl and aryloxyalkyl phosphonates and use as antiviral age Arylalkyl and aryloxyalkyl phosphonates and use as antiviral age

1978-06-05

1980-01-08

Sutto, Anton H.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

260941, 260951, 260952, 424212, A01N 936, C07F 940

Patent

active

041827597

ABSTRACT:
Arylalkyl and aryloxyalkylphosphonates, useful as antiviral agents, are prepared by reacting an arylalkyl or aryloxyalkyl halide with a trialkyl phosphite, or with an alkali metal salt of a dialkyl phosphonate, trialkyl phosphonoalkanoate or dialkyl phosphonoalkanone.

REFERENCES:
patent: 2934507 (1960-04-01), Chadwick et al.
patent: 3917718 (1975-11-01), Collins
patent: 4031246 (1977-06-01), Collins et al.
Baron et al., "Annual Reports in Medicinal Chemistry", Chapter on Antiviral Agents, vol. 10, (1970), p. 166.
Linn et al., "J. Am. Chem. Soc.", vol. 87 (1965), pp. 3657-3672.

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