Aryl sulfonamides useful as inhibitors of chemokine receptor...

Details Aryl sulfonamides useful as inhibitors of chemokine receptor... Aryl sulfonamides useful as inhibitors of chemokine receptor...

2004-07-14

2009-02-17

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S158000, C546S169000, C544S129000, C544S298000

Reexamination Certificate

active

07491827

ABSTRACT:
The present invention provides compounds of general formula I:or a pharmaceutically acceptable salt thereof, wherein R1, X, Z, R2, X1, Ar, n, R3and R4are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR8 and accordingly are useful for the treatment of a variety of inflammatory and allergic disorders.

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