Aryl-substituted pyridylalkane, alkene, and alkine...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S089000, C514S344000, C514S348000, C514S349000, C514S350000, C514S351000, C514S352000, C514S354000, C514S355000, C514S356000, C546S022000, C546S024000, C546S285000, C546S286000, C546S287000, C546S288000, C546S289000, C546S290000, C546S296000, C546S297000, C546S300000, C546S309000, C546S310000, C546S312000, C546S315000, C546S316000, C546S318000, C546S321000, C546S322000, C546S323000, C546S326000, C546S328000, C546S330000, C546S332000, C546S335000, C546S337000

Reexamination Certificate

active

09596086

ABSTRACT:
The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group, methods for the synthesis of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.

REFERENCES:
patent: 4283541 (1981-08-01), Shroff et al.
patent: 5169856 (1992-12-01), Goto et al.
patent: 5260323 (1993-11-01), Baader et al.
patent: 5326772 (1994-07-01), Klemm et al.
patent: 5925527 (1999-07-01), Hayes et al.
patent: 6313153 (2001-11-01), Hasegawa et al.
patent: 6506572 (2003-01-01), Biedermann et al.
patent: 2085954 (1993-06-01), None
patent: 4020570 (1992-01-01), None
patent: 048045 (1982-03-01), None
patent: 210782 (1987-02-01), None
patent: 271023 (1988-06-01), None
patent: 330026 (1989-08-01), None
patent: 343307 (1989-11-01), None
patent: 416581 (1991-03-01), None
patent: 471236 (1992-02-01), None
patent: 479601 (1992-04-01), None
patent: 522606 (1993-01-01), None
patent: 530444 (1993-03-01), None
patent: 548883 (1993-06-01), None
patent: 512902 (1994-04-01), None
patent: 428434 (1994-05-01), None
patent: 2304714 (1998-11-01), None
patent: 57136518 (1982-08-01), None
patent: 63179869 (1988-07-01), None
patent: WO89/07443 (1989-08-01), None
patent: WO91/15484 (1991-10-01), None
patent: WO91/15485 (1991-10-01), None
patent: WO93/14113 (1993-07-01), None
patent: WO95/10514 (1995-04-01), None
patent: WO95/10515 (1995-04-01), None
patent: WO96/31478 (1996-10-01), None
patent: WO97/48695 (1997-01-01), None
patent: WO97/48397 (1997-12-01), None
patent: WO 98/34111 (1998-08-01), None
CAPLUS printout of the references cited in the attached office action, 2002.
Nishikawa et al., “Acrylamide Derivatives as Antiallergic Agents. 2. Synthesis and Structure-Activity Relationships of N-[4-[4-(Diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl) acrylamides” Chem. Pharm. Bull. 37(1) 100-105 (1989).
Nishikawa et al., “Acrylamide Derivatives as Antiallergic Agents. 2. Synthesis and Structure-Activity Relationships of N-[4-[4-(Diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl) acrylamides” J. Med. Chem. 1989, 32, 583-593.
Ishihara et al., “Central Cholinergic Agents. II. Synthesis and Acetylcholinesterase Inhibitory Activities of N-[w-[N-Alkyl-N-(phenylmethyl) amino]alkyl]-3-arylpropenamides” Chem. Pharm. Bull. 39 (12) 3236-3234 (1991).
Ross, “The Preparation of Some 4-Substituted Nicotinic Acids and Nicotinamides” J. Chem. Soc. (C), 1966, 1816-1820.
M. Eder, P. Gedigk, (Ed.) “Allgemeine Pathologie und Pathologische Anatomie”, Springer Verlag, Berlin, 33rd Ed., 1990, pp. 208-213 and translation of relevant passages thereof.
Chemical Abstracts, vol. 124, No. 13, 1996, p. 1004, 1730 15r.
Chemical Abstracts, vol. 115, 1991, p. 48, 150041w.
Chemical Abstracts, vol. 114, 1991, p. 714, 101646t.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Aryl-substituted pyridylalkane, alkene, and alkine... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aryl-substituted pyridylalkane, alkene, and alkine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aryl-substituted pyridylalkane, alkene, and alkine... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3912506

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.